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Enclomiphene citrate tablets by Sigma Pharmaceuticals
Male Health

Androxal®

Enclomiphene 12.5 mg

Enclomiphene citrate is a refined, single-isomer alternative to Clomid, developed specifically for men with secondary hypogonadism and low testosterone. Enclomiphene raises natural testosterone while helping preserve fertility.

Active ingredient
Enclomiphene
Strength
12.5 mg
Form
Solid Tablets
Pack
50 tablets (1 blisters × 50)
Category
Male Health
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Product information

Product Overview

Enclomiphene citrate is a refined, single-isomer form of clomiphene citrate (Clomid), developed specifically for men with secondary hypogonadism and low testosterone. Unlike testosterone therapy, enclomiphene does not supply testosterone directly but stimulates the body's own testosterone production while supporting spermatogenesis.

Enclomiphene vs. Clomid

Clomid (clomiphene citrate) is a mixture of two isomers: approximately 62% enclomiphene and 38% zuclomiphene. Enclomiphene contains only the isomer responsible for raising LH, FSH, and testosterone.

EnclomipheneClomid (Clomiphene)
CompositionSingle isomer (enclomiphene only)Enclomiphene + zuclomiphene
Estrogenic activityAnti-estrogenic at the hypothalamusContains zuclomiphene, which has weak estrogenic activity
Half-lifeShort (about 10 hours)Zuclomiphene persists for weeks and can accumulate
Primary focusStudied for male secondary hypogonadismApproved for female ovulatory infertility; used off-label in men

By removing zuclomiphene, enclomiphene is designed to deliver the testosterone-raising effect of Clomid while avoiding the accumulation of an estrogenic isomer that may contribute to side effects such as mood changes.

Third-party lab reports

No lab reports have been published for this product yet. All lab reports →